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TV Guide for E4 on Sunday 21st March 2010
| Time | E4 |
| 0 | |
| 1 | 01:10 Supernanny Jo Frost is on a mission to help four-year-old Cameron and his parents control his aggressive and disruptive behaviour. |
| 2 | 02:10 Gok's Fashion Fix In the final programme in the series, Gok catches up with Jamelia in her hometown of Birmingham for a spot of retail therapy and to talk designer shoes. |
| 3 | 03:05 Samantha Who? In the season finale, Andrea and Regina disagree repeatedly over how to plan Samantha's birthday party. 03:25Hollyoaks Omnibus Josh walks in on Rhys and India about to kiss, and goes into one. Calvin is furious to find Lauren and Gaz semi-naked in her bedroom, and throws Gaz out. [S,SL] |
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| 5 | |
| 6 | 06:00 Wife Swap USA A wife who has three macho boys who love running wild in a nearby swamp swaps with a mum whose son has been brought up to enjoy the finer things in life including ballet, cheese and opera. 06:55Wife Swap USA A family of easy-going gym-enthusiasts swap rules with a prim family who hold tea parties. |
| 7 | 07:50 Supernanny Dr Stephen Brickley and Dr Ann Gormley both have PHDs in neuroscience, but when it comes to controlling their two sets of twins - all under the age of five - they've run out of ideas. |
| 8 | 08:50 Gok's Fashion Fix Gok takes on designer clothes chosen by the most powerful fashion buyers with a collection he's sourced entirely from the high street and Alexa Chung puts high heels through their paces. |
| 9 | 09:55 Wife Swap USA A wife who has three macho boys who love running wild in a nearby swamp swaps with a mum whose son has been brought up to enjoy the finer things in life including ballet, cheese and opera. |
| 10 | 10:50 Wife Swap USA A family of easy-going gym-enthusiasts swap rules with a prim family who hold tea parties. |
| 11 | 11:50 How To Look Good Naked 25-year-old Rubie Poonia hates her size 18 body and thinks it's too big to be beautiful. Gok's mission is to give Rubie the style and confidence to feel differently about herself |
| 12 | 12:20 Roswell When Max is fascinated by an intriguing autistic child he wonders if his own lost child is attempting to reach out to him. |
| 13 | 13:15 Roswell In an attempt to find Roswell's legendary New Year's Rave, Max and Maria join forces. |
| 14 | 14:05 Reaper Satan transforms Sam into a white dove for his next mission, which is to track down an escaped magician who kills anyone who doesn't like his magic act. [AD,S] 14:55The First Wives Club Bette Midler, Goldie Hawn and Diane Keaton play three wives, ditched by their husbands for newer models, who vow revenge by hitting the men in their pockets. |
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| 17 | 17:00 Friends At the funeral of her grandmother, Phoebe is astounded to meet her biological father, and Joey's fondness for an expensive bag loses him a job. [AD,S] 17:30Friends Chandler and Monica's relationship becomes less of a secret, and Ross must prove to his boss that he's sane in order to return to work. |
| 18 | 18:00 Scrubs Carla worries she's losing her identity and that as a result her daughter will not know her Latin heritage. 18:30Scrubs The Sacred Heart staff have to deal with their inner child when JD and Turk remember their first prank and Dr Kelso celebrates his birthday. |
| 19 | 19:00 My Name Is Earl Earl visits a TV reporter whose career was destroyed by his and Randy's protracted tomfoolery. 19:30My Name Is Earl When Richard Chubby (Burt Reynolds), Camden's most powerful businessman, dies in a freak accident, his son Little Chubby comes back to town. 19:55Friends At the funeral of her grandmother, Phoebe is astounded to meet her biological father, and Joey's fondness for an expensive bag loses him a job. [AD,S] |
| 20 | 20:30 Friends Chandler and Monica's relationship becomes less of a secret, and Ross must prove to his boss that he's sane in order to return to work. |
| 21 | 21:00 Desperate Housewives Susan discovers a surprising connection between Mike and Katherine, leading her to question her relationship with Mike. [AD,S] |
| 22 | 22:00 Desperate Housewives Angie leaves Wisteria Lane in the wake of another attack, Susan finds out about Bree's affair and confronts her and Katherine has an emotional breakdown. [AD,S] |
| 23 | 23:00 Samantha Who? In the season finale, Andrea and Regina disagree repeatedly over how to plan Samantha's birthday party. 23:25Samantha Who? Regina's old enemy is in a dance competition, and Regina desperately wants to beat her, but she needs Sam's help. 23:55Being Erica Erica seeks her sister Samantha's forgiveness as Yom Kippur approaches. Dr Tom encourages Erica to forgive her parents. |